Dynamic phosphoregulation of the cortical actin cytoskeleton and endocytic machinery revealed by real-time chemical genetic analysis

We used chemical genetics to control the activity of budding yeast Prk1p, which is a protein kinase that is related to mammalian GAK and AAK1, and which targets several actin regulatory proteins implicated in endocytosis. In vivo Prk1p inhibition blocked pheromone receptor endocytosis, and caused co...

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Detalles Bibliográficos
Autores principales: Sekiya-Kawasaki, Mariko, Groen, Aaron Chris, Cope, M. Jamie T.V., Kaksonen, Marko, Watson, Hadiya A., Zhang, Chao, Shokat, Kevan M., Wendland, Beverly, McDonald, Kent L., McCaffery, J. Michael, Drubin, David G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172809/
https://www.ncbi.nlm.nih.gov/pubmed/12952930
http://dx.doi.org/10.1083/jcb.200305077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172809/
https://www.ncbi.nlm.nih.gov/pubmed/12952930
http://dx.doi.org/10.1083/jcb.200305077

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