Differential αv integrin–mediated Ras-ERK signaling during two pathways of angiogenesis

Antagonists of αvβ3 and αvβ5 disrupt angiogenesis in response to bFGF and VEGF, respectively. Here, we show that these αv integrins differentially contribute to sustained Ras-extracellular signal–related kinase (Ras-ERK) signaling in blood vessels, a requirement for endothelial cell survival and ang...

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Detalles Bibliográficos
Autores principales: Hood, John D., Frausto, Ricardo, Kiosses, William B., Schwartz, Martin A., Cheresh, David A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172815/
https://www.ncbi.nlm.nih.gov/pubmed/12952943
http://dx.doi.org/10.1083/jcb.200304105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172815/
https://www.ncbi.nlm.nih.gov/pubmed/12952943
http://dx.doi.org/10.1083/jcb.200304105

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