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Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity

We provide genetic evidence defining a role for noncanonical Wnt function in vertebrate axis formation. In zebrafish, misexpression of Wnt-4, -5, and -11 stimulates calcium (Ca(2+)) release, defining the Wnt/Ca(2+) class. We describe genetic interaction between two Wnt/Ca(2+) members, Wnt-5 (pipetai...

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Detalles Bibliográficos
Autores principales: Westfall, Trudi A., Brimeyer, Ryan, Twedt, Jen, Gladon, Jean, Olberding, Andrea, Furutani-Seiki, Makoto, Slusarski, Diane C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172822/
https://www.ncbi.nlm.nih.gov/pubmed/12952939
http://dx.doi.org/10.1083/jcb.200303107