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Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/β-catenin activity
We provide genetic evidence defining a role for noncanonical Wnt function in vertebrate axis formation. In zebrafish, misexpression of Wnt-4, -5, and -11 stimulates calcium (Ca(2+)) release, defining the Wnt/Ca(2+) class. We describe genetic interaction between two Wnt/Ca(2+) members, Wnt-5 (pipetai...
Autores principales: | Westfall, Trudi A., Brimeyer, Ryan, Twedt, Jen, Gladon, Jean, Olberding, Andrea, Furutani-Seiki, Makoto, Slusarski, Diane C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172822/ https://www.ncbi.nlm.nih.gov/pubmed/12952939 http://dx.doi.org/10.1083/jcb.200303107 |
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