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Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells
A mitosis-specific Aurora-A kinase has been implicated in microtubule organization and spindle assembly in diverse organisms. However, exactly how Aurora-A controls the microtubule nucleation onto centrosomes is unknown. Here, we show that Aurora-A specifically binds to the COOH-terminal domain of a...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172831/ https://www.ncbi.nlm.nih.gov/pubmed/12939255 http://dx.doi.org/10.1083/jcb.200305048 |