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Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte–specific expression in vivo

The α1(X) collagen gene (Col10a1) is the only known hypertrophic chondrocyte–specific molecular marker. Until recently, few transcriptional factors specifying its tissue-specific expression have been identified. We show here that a 4-kb murine Col10a1 promoter can drive β-galactosidase expression in...

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Detalles Bibliográficos
Autores principales: Zheng, Qiping, Zhou, Guang, Morello, Roy, Chen, Yuqing, Garcia-Rojas, Xavier, Lee, Brendan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172833/
https://www.ncbi.nlm.nih.gov/pubmed/12952936
http://dx.doi.org/10.1083/jcb.200211089