The conditional inactivation of the β-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility

Using the Cre/loxP system we conditionally inactivated β-catenin in endothelial cells. We found that early phases of vasculogenesis and angiogenesis were not affected in mutant embryos; however, vascular patterning in the head, vitelline, umbilical vessels, and the placenta was altered. In addition,...

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Detalles Bibliográficos
Autores principales: Cattelino, Anna, Liebner, Stefan, Gallini, Radiosa, Zanetti, Adriana, Balconi, Giovanna, Corsi, Alessandro, Bianco, Paolo, Wolburg, Hartwig, Moore, Robert, Oreda, Boussadia, Kemler, Rolf, Dejana, Elisabetta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172846/
https://www.ncbi.nlm.nih.gov/pubmed/12975353
http://dx.doi.org/10.1083/jcb.200212157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172846/
https://www.ncbi.nlm.nih.gov/pubmed/12975353
http://dx.doi.org/10.1083/jcb.200212157

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