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The conditional inactivation of the β-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility
Using the Cre/loxP system we conditionally inactivated β-catenin in endothelial cells. We found that early phases of vasculogenesis and angiogenesis were not affected in mutant embryos; however, vascular patterning in the head, vitelline, umbilical vessels, and the placenta was altered. In addition,...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172846/ https://www.ncbi.nlm.nih.gov/pubmed/12975353 http://dx.doi.org/10.1083/jcb.200212157 |