The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes

Actin (thin) filament length regulation and stability are essential for striated muscle function. To determine the role of the actin filament pointed end capping protein, tropomodulin1 (Tmod1), with tropomyosin, we generated monoclonal antibodies (mAb17 and mAb8) against Tmod1 that specifically disr...

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Detalles Bibliográficos
Autores principales: Mudry, Ryan E., Perry, Cynthia N., Richards, Meredith, Fowler, Velia M., Gregorio, Carol C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172850/
https://www.ncbi.nlm.nih.gov/pubmed/12975349
http://dx.doi.org/10.1083/jcb.200305031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172850/
https://www.ncbi.nlm.nih.gov/pubmed/12975349
http://dx.doi.org/10.1083/jcb.200305031

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