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The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes
Actin (thin) filament length regulation and stability are essential for striated muscle function. To determine the role of the actin filament pointed end capping protein, tropomodulin1 (Tmod1), with tropomyosin, we generated monoclonal antibodies (mAb17 and mAb8) against Tmod1 that specifically disr...
Autores principales: | Mudry, Ryan E., Perry, Cynthia N., Richards, Meredith, Fowler, Velia M., Gregorio, Carol C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172850/ https://www.ncbi.nlm.nih.gov/pubmed/12975349 http://dx.doi.org/10.1083/jcb.200305031 |
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