Myostatin negatively regulates satellite cell activation and self-renewal

Satellite cells are quiescent muscle stem cells that promote postnatal muscle growth and repair. Here we show that myostatin, a TGF-β member, signals satellite cell quiescence and also negatively regulates satellite cell self-renewal. BrdU labeling in vivo revealed that, among the Myostatin-deficien...

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Detalles Bibliográficos
Autores principales: McCroskery, Seumas, Thomas, Mark, Maxwell, Linda, Sharma, Mridula, Kambadur, Ravi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172861/
https://www.ncbi.nlm.nih.gov/pubmed/12963705
http://dx.doi.org/10.1083/jcb.200207056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172861/
https://www.ncbi.nlm.nih.gov/pubmed/12963705
http://dx.doi.org/10.1083/jcb.200207056

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