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Myostatin negatively regulates satellite cell activation and self-renewal
Satellite cells are quiescent muscle stem cells that promote postnatal muscle growth and repair. Here we show that myostatin, a TGF-β member, signals satellite cell quiescence and also negatively regulates satellite cell self-renewal. BrdU labeling in vivo revealed that, among the Myostatin-deficien...
Autores principales: | McCroskery, Seumas, Thomas, Mark, Maxwell, Linda, Sharma, Mridula, Kambadur, Ravi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172861/ https://www.ncbi.nlm.nih.gov/pubmed/12963705 http://dx.doi.org/10.1083/jcb.200207056 |
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