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GDNF promotes tubulogenesis of GFRα1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase

Glial cell line–derived neurotrophic factor (GDNF) and hepatocyte growth factor (HGF) are multifunctional signaling molecules in embryogenesis. HGF binds to and activates Met receptor tyrosine kinase. The signaling receptor complex for GDNF typically includes both GDNF family receptor α1 (GFRα1) and...

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Detalles Bibliográficos
Autores principales: Popsueva, Anna, Poteryaev, Dmitry, Arighi, Elena, Meng, Xiaojuan, Angers-Loustau, Alexandre, Kaplan, David, Saarma, Mart, Sariola, Hannu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172872/
https://www.ncbi.nlm.nih.gov/pubmed/12682085
http://dx.doi.org/10.1083/jcb.200212174