Cargando…

GDNF promotes tubulogenesis of GFRα1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase

Glial cell line–derived neurotrophic factor (GDNF) and hepatocyte growth factor (HGF) are multifunctional signaling molecules in embryogenesis. HGF binds to and activates Met receptor tyrosine kinase. The signaling receptor complex for GDNF typically includes both GDNF family receptor α1 (GFRα1) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Popsueva, Anna, Poteryaev, Dmitry, Arighi, Elena, Meng, Xiaojuan, Angers-Loustau, Alexandre, Kaplan, David, Saarma, Mart, Sariola, Hannu
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172872/ https://www.ncbi.nlm.nih.gov/pubmed/12682085 http://dx.doi.org/10.1083/jcb.200212174

Ejemplares similares

Enhancement of HGF-induced tubulogenesis by endothelial cell-derived GDNF
por: Nakasatomi, Masao, et al.
Publicado: (2019)

Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro
por: Saarenpää, Tuulia, et al.
Publicado: (2017)

RET-independent signaling by GDNF ligands and GFRα receptors
por: Ibáñez, Carlos F., et al.
Publicado: (2020)

APE1 Promotes Pancreatic Cancer Proliferation through GFRα1/Src/ERK Axis-Cascade Signaling in Response to GDNF
por: Choi, Yoo-Duk, et al.
Publicado: (2020)

Small-Molecule Ligands as Potential GDNF Family Receptor Agonists
por: Ivanova, Larisa, et al.
Publicado: (2018)

Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis
por: Li, Peixin, et al.
Publicado: (2018)

Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly
por: Houghton, F. M., et al.
Publicado: (2023)

Development of the urogenital system is regulated via the 3′UTR of GDNF
por: Li, Hao, et al.
Publicado: (2019)

Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility
por: Li, Ran, et al.
Publicado: (2015)

GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway
por: Yu, Li-Ying, et al.
Publicado: (2003)

Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease
por: Penttinen, Anna-Maija, et al.
Publicado: (2018)

TGFβ induces GDNF responsiveness in neurons by recruitment of GFRα1 to the plasma membrane
por: Peterziel, H., et al.
Publicado: (2002)

GDNF Receptor Agonist Alleviates Motor Imbalance in Unilateral 6-Hydroxydopamine Model of Parkinson’s Disease
por: Renko, Juho-Matti, et al.
Publicado: (2020)

Tip cells: Master regulators of tubulogenesis?
por: Weavers, Helen, et al.
Publicado: (2014)

Simultaneous Detection of Both GDNF and GFRα1 Expression Patterns in the Mouse Central Nervous System
por: Ortega-de San Luis, Clara, et al.
Publicado: (2016)

Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function
por: Fernández-Suárez, Diana, et al.
Publicado: (2021)

Characterization of Drosophila GDNF Receptor-Like and Evidence for Its Evolutionarily Conserved Interaction with Neural Cell Adhesion Molecule (NCAM)/FasII
por: Kallijärvi, Jukka, et al.
Publicado: (2012)

Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin
por: Bespalov, Maxim M., et al.
Publicado: (2011)

Data on in vivo phenotypes of GFRα1-positive spermatogonia stimulated by interstitial GDNF signals in mouse testes
por: Uchida, Aya, et al.
Publicado: (2016)

GDNF/GFRα1 Complex Abrogates Self-Renewing Activity of Cortical Neural Precursors Inducing Their Differentiation
por: Bonafina, Antonela, et al.
Publicado: (2018)

Induction of GDNF and GFRα-1 Following AAV1-Rheb(S16H) Administration in the Hippocampus in vivo
por: Yun, Dongyoung, et al.
Publicado: (2020)

Requirement of focal adhesion kinase in branching tubulogenesis
por: Wei, Wei-Chun, et al.
Publicado: (2009)

Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson’s Disease
por: Garea-Rodríguez, Enrique, et al.
Publicado: (2016)

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential
por: Yadav, Leena, et al.
Publicado: (2020)

Mutation and deletion analysis of GFRα-1, encoding the co-receptor for the GDNF/RET complex, in human brain tumours
por: Gimm, O, et al.
Publicado: (1999)

Role of GDNF, GFRα1 and GFAP in a Bifidobacterium-Intervention Induced Mouse Model of Intestinal Neuronal Dysplasia
por: Liu, Wei, et al.
Publicado: (2022)

Geometrical Microfeature Cues for Directing Tubulogenesis of Endothelial Cells
por: Lei, Yifeng, et al.
Publicado: (2012)

The role of the exocyst in renal ciliogenesis, cystogenesis, tubulogenesis, and development
por: Lipschutz, Joshua H.
Publicado: (2019)

Evidence for an Additive Neurorestorative Effect of Simultaneously Administered CDNF and GDNF in Hemiparkinsonian Rats: Implications for Different Mechanism of Action
por: Voutilainen, Merja H., et al.
Publicado: (2017)

Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands
por: Ivanova, Larisa, et al.
Publicado: (2018)

Metastasis Update: Human Prostate Carcinoma Invasion via Tubulogenesis
por: Nagle, Raymond B., et al.
Publicado: (2011)

Pdx1 regulates pancreas tubulogenesis and E-cadherin expression
por: Marty-Santos, Leilani, et al.
Publicado: (2016)

Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning
por: Sergaki, Maria Christina, et al.
Publicado: (2017)

Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells
por: Hall, Bonnie L., et al.
Publicado: (2020)

Dynamics of β-Catenin Interactions with APC Protein Regulate Epithelial Tubulogenesis
por: Pollack, Anne L., et al.
Publicado: (1997)

Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation
por: Jia, Liwei, et al.
Publicado: (2011)

Three-dimensional reconstructions of intrahepatic bile duct tubulogenesis in human liver
por: Vestentoft, Peter S, et al.
Publicado: (2011)

Molecular mechanisms of tubulogenesis revealed in the sea star hydro-vascular organ
por: Perillo, Margherita, et al.
Publicado: (2023)

Nuclear Functions of the Tyrosine Kinase Src
por: Bagnato, Giulia, et al.
Publicado: (2020)

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
por: Adams, Sarah E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_u20nh6v0l06uo6q2slpstso27i