Arrest of mammalian fibroblasts in G1 in response to actin inhibition is dependent on retinoblastoma pocket proteins but not on p53

p53 and the retinoblastoma (RB) pocket proteins are central to the control of progression through the G1 phase of the cell cycle. The RB pocket protein family is downstream of p53 and controls S-phase entry. Disruption of actin assembly arrests nontransformed mammalian fibroblasts in G1. We show tha...

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Detalles Bibliográficos
Autores principales: Lohez, Olivier D., Reynaud, Caroline, Borel, Franck, Andreassen, Paul R., Margolis, Robert L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172876/
https://www.ncbi.nlm.nih.gov/pubmed/12682090
http://dx.doi.org/10.1083/jcb.200208140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172876/
https://www.ncbi.nlm.nih.gov/pubmed/12682090
http://dx.doi.org/10.1083/jcb.200208140

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