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Phospholipase Cδ4 is required for Ca(2+) mobilization essential for acrosome reaction in sperm

Zona pellucida (ZP)–induced acrosome reaction in sperm is a required step for mammalian fertilization. However, the precise mechanism of the acrosome reaction remains unclear. We previously reported that PLCδ4 is involved in the ZP-induced acrosome reaction in mouse sperm. Here we have monitored Ca(...

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Detalles Bibliográficos
Autores principales: Fukami, Kiyoko, Yoshida, Manabu, Inoue, Takafumi, Kurokawa, Manabu, Fissore, Rafael A., Yoshida, Nobuaki, Mikoshiba, Katsuhiko, Takenawa, Tadaomi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172882/
https://www.ncbi.nlm.nih.gov/pubmed/12695499
http://dx.doi.org/10.1083/jcb.200210057