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Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin α5 in the glomerular basement membrane

In developing glomeruli, laminin α5 replaces laminin α1 in the glomerular basement membrane (GBM) at the capillary loop stage, a transition required for glomerulogenesis. To investigate domain-specific functions of laminin α5 during glomerulogenesis, we produced transgenic mice that express a chimer...

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Detalles Bibliográficos
Autores principales: Kikkawa, Yamato, Virtanen, Ismo, Miner, Jeffrey H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172883/
https://www.ncbi.nlm.nih.gov/pubmed/12682087
http://dx.doi.org/10.1083/jcb.200211121