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RPTP-α acts as a transducer of mechanical force on α(v)/β(3)-integrin–cytoskeleton linkages
Cell motility on ECM critically depends on the cellular response to force from the matrix. We find that force-dependent reinforcement of α(v)/β(3)-integrin–mediated cell–matrix connections requires the receptor-like tyrosine phosphatase α (RPTPα). RPTPα colocalizes with α(v)-integrins at the leading...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172891/ https://www.ncbi.nlm.nih.gov/pubmed/12682088 http://dx.doi.org/10.1083/jcb.200211061 |