Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

Chemokines arrest circulating lymphocytes within the vasculature through the rapid up-regulation of leukocyte integrin adhesive activity, promoting subsequent lymphocyte transmigration. However, the key regulatory molecules regulating this process have remained elusive. Here, we demonstrate that Rap...

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Detalles Bibliográficos
Autores principales: Shimonaka, Mika, Katagiri, Koko, Nakayama, Toshinori, Fujita, Naoya, Tsuruo, Takashi, Yoshie, Osamu, Kinashi, Tatsuo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172897/
https://www.ncbi.nlm.nih.gov/pubmed/12707305
http://dx.doi.org/10.1083/jcb.200301133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172897/
https://www.ncbi.nlm.nih.gov/pubmed/12707305
http://dx.doi.org/10.1083/jcb.200301133

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