Cargando…

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

Chemokines arrest circulating lymphocytes within the vasculature through the rapid up-regulation of leukocyte integrin adhesive activity, promoting subsequent lymphocyte transmigration. However, the key regulatory molecules regulating this process have remained elusive. Here, we demonstrate that Rap...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimonaka, Mika, Katagiri, Koko, Nakayama, Toshinori, Fujita, Naoya, Tsuruo, Takashi, Yoshie, Osamu, Kinashi, Tatsuo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172897/
https://www.ncbi.nlm.nih.gov/pubmed/12707305
http://dx.doi.org/10.1083/jcb.200301133

Ejemplares similares