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Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
Chemokines arrest circulating lymphocytes within the vasculature through the rapid up-regulation of leukocyte integrin adhesive activity, promoting subsequent lymphocyte transmigration. However, the key regulatory molecules regulating this process have remained elusive. Here, we demonstrate that Rap...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172897/ https://www.ncbi.nlm.nih.gov/pubmed/12707305 http://dx.doi.org/10.1083/jcb.200301133 |