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FAK induces expression of Prx1 to promote tenascin-C–dependent fibroblast migration

Fibroblast migration depends, in part, on activation of FAK and cellular interactions with tenascin-C (TN-C). Consistent with the idea that FAK regulates TN-C, migration-defective FAK-null cells expressed reduced levels of TN-C. Furthermore, expression of FAK in FAK-null fibroblasts induced TN-C, wh...

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Detalles Bibliográficos
Autores principales: McKean, David M., Sisbarro, Lila, Ilic, Dusko, Kaplan-Alburquerque, Nihal, Nemenoff, Raphael, Weiser-Evans, Mary, Kern, Michael J., Jones, Peter Lloyd
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172901/
https://www.ncbi.nlm.nih.gov/pubmed/12741393
http://dx.doi.org/10.1083/jcb.jcb.200302126