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Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis

Lysosome-related organelles are cell type–specific intracellular compartments with distinct morphologies and functions. The molecular mechanisms governing the formation of their unique structural features are not known. Melanosomes and their precursors are lysosome-related organelles that are charac...

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Detalles Bibliográficos
Autores principales: Berson, Joanne F., Theos, Alexander C., Harper, Dawn C., Tenza, Danielle, Raposo, Graça, Marks, Michael S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172928/
https://www.ncbi.nlm.nih.gov/pubmed/12732614
http://dx.doi.org/10.1083/jcb.200302072