Holey barrier: claudins and the regulation of brain endothelial permeability

Endothelial tight junctions (TJs) are an important functional part of the blood-brain barrier (BBB). In this issue, Nitta et al. (2003) demonstrate that claudin-5, a transmembrane protein of TJs, is a critical determinant of BBB permeability in mice. Unexpectedly, knockout of claudin-5 did not resul...

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Detalles Bibliográficos
Autores principales: Matter, Karl, Balda, Maria S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172932/
https://www.ncbi.nlm.nih.gov/pubmed/12743096
http://dx.doi.org/10.1083/jcb.200304039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172932/
https://www.ncbi.nlm.nih.gov/pubmed/12743096
http://dx.doi.org/10.1083/jcb.200304039

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