A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

Signals transduced by kinases depend on the extent and duration of substrate phosphorylation. We generated genetically encoded fluorescent reporters for PKC activity that reversibly respond to stimuli activating PKC. Specifically, phosphorylation of the reporter expressed in mammalian cells causes c...

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Detalles Bibliográficos
Autores principales: Violin, Jonathan D., Zhang, Jin, Tsien, Roger Y., Newton, Alexandra C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172956/
https://www.ncbi.nlm.nih.gov/pubmed/12782683
http://dx.doi.org/10.1083/jcb.200302125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172956/
https://www.ncbi.nlm.nih.gov/pubmed/12782683
http://dx.doi.org/10.1083/jcb.200302125

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