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Back signaling by the Nrg-1 intracellular domain

Transmembrane isoforms of neuregulin-1 (Nrg-1), ligands for erbB receptors, include an extracellular domain with an EGF-like sequence and a highly conserved intracellular domain (ICD) of unknown function. In this paper, we demonstrate that transmembrane isoforms of Nrg-1 are bidirectional signaling...

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Detalles Bibliográficos
Autores principales: Bao, Jianxin, Wolpowitz, Deon, Role, Lorna W., Talmage, David A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172983/
https://www.ncbi.nlm.nih.gov/pubmed/12821646
http://dx.doi.org/10.1083/jcb.200212085