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Back signaling by the Nrg-1 intracellular domain
Transmembrane isoforms of neuregulin-1 (Nrg-1), ligands for erbB receptors, include an extracellular domain with an EGF-like sequence and a highly conserved intracellular domain (ICD) of unknown function. In this paper, we demonstrate that transmembrane isoforms of Nrg-1 are bidirectional signaling...
Autores principales: | Bao, Jianxin, Wolpowitz, Deon, Role, Lorna W., Talmage, David A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172983/ https://www.ncbi.nlm.nih.gov/pubmed/12821646 http://dx.doi.org/10.1083/jcb.200212085 |
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