Cargando…

Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

Akey step in lipolytic activation of adipocytes is the translocation of hormone-sensitive lipase (HSL) from the cytosol to the surface of the lipid storage droplet. Adipocytes from perilipin-null animals have an elevated basal rate of lipolysis compared with adipocytes from wild-type mice, but fail...

Descripción completa

Detalles Bibliográficos
Autores principales: Sztalryd, Carole, Xu, Guoheng, Dorward, Heidi, Tansey, John T., Contreras, Juan A., Kimmel, Alan R., Londos, Constantine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172984/
https://www.ncbi.nlm.nih.gov/pubmed/12810697
http://dx.doi.org/10.1083/jcb.200210169