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Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation
Akey step in lipolytic activation of adipocytes is the translocation of hormone-sensitive lipase (HSL) from the cytosol to the surface of the lipid storage droplet. Adipocytes from perilipin-null animals have an elevated basal rate of lipolysis compared with adipocytes from wild-type mice, but fail...
Autores principales: | Sztalryd, Carole, Xu, Guoheng, Dorward, Heidi, Tansey, John T., Contreras, Juan A., Kimmel, Alan R., Londos, Constantine |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172984/ https://www.ncbi.nlm.nih.gov/pubmed/12810697 http://dx.doi.org/10.1083/jcb.200210169 |
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