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Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis

Grb2-associated binder 2 (Gab2), a member of the Dos/Gab subfamily scaffolding molecules, plays important roles in regulating the growth, differentiation, and function of many hematopoietic cell types. In this paper, we reveal a novel function of Gab2 in Fcγ receptor (FcγR)–initiated phagocytosis in...

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Detalles Bibliográficos
Autores principales: Gu, Haihua, Botelho, Roberto J., Yu, Min, Grinstein, Sergio, Neel, Benjamin G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172986/
https://www.ncbi.nlm.nih.gov/pubmed/12821647
http://dx.doi.org/10.1083/jcb.200212158