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Ergosterol is required for targeting of tryptophan permease to the yeast plasma membrane

It was known that the uptake of tryptophan is reduced in the yeast erg6 mutant, which is defective in a late step of ergosterol biosynthesis. Here, we show that this is because the high affinity tryptophan permease Tat2p is not targeted to the plasma membrane. In wild-type cells, the plasma membrane...

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Detalles Bibliográficos
Autores principales: Umebayashi, Kyohei, Nakano, Akihiko
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172991/
https://www.ncbi.nlm.nih.gov/pubmed/12810702
http://dx.doi.org/10.1083/jcb.200303088