Low density lipoprotein receptor–related protein is a calreticulin coreceptor that signals focal adhesion disassembly

Thrombospondin (TSP) signals focal adhesion disassembly (the intermediate adhesive state) through interactions with cell surface calreticulin (CRT). TSP or a peptide (hep I) of the active site induces focal adhesion disassembly through binding to CRT, which activates phosphoinositide 3-kinase (PI3K)...

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Detalles Bibliográficos
Autores principales: Orr, Anthony Wayne, Pedraza, Claudio E., Pallero, Manuel Antonio, Elzie, Carrie A., Goicoechea, Silvia, Strickland, Dudley K., Murphy-Ullrich, Joanne E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172996/
https://www.ncbi.nlm.nih.gov/pubmed/12821648
http://dx.doi.org/10.1083/jcb.200302069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172996/
https://www.ncbi.nlm.nih.gov/pubmed/12821648
http://dx.doi.org/10.1083/jcb.200302069

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