Cargando…
Low density lipoprotein receptor–related protein is a calreticulin coreceptor that signals focal adhesion disassembly
Thrombospondin (TSP) signals focal adhesion disassembly (the intermediate adhesive state) through interactions with cell surface calreticulin (CRT). TSP or a peptide (hep I) of the active site induces focal adhesion disassembly through binding to CRT, which activates phosphoinositide 3-kinase (PI3K)...
Autores principales: | Orr, Anthony Wayne, Pedraza, Claudio E., Pallero, Manuel Antonio, Elzie, Carrie A., Goicoechea, Silvia, Strickland, Dudley K., Murphy-Ullrich, Joanne E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172996/ https://www.ncbi.nlm.nih.gov/pubmed/12821648 http://dx.doi.org/10.1083/jcb.200302069 |
Ejemplares similares
-
Calreticulin is important for the development of renal fibrosis and dysfunction in diabetic nephropathy
por: Lu, Ailing, et al.
Publicado: (2020) -
The small GTPase RhoG regulates microtubule-mediated focal adhesion disassembly
por: Zinn, Ashtyn, et al.
Publicado: (2019) -
Actomyosin contractility and buckling of microtubules in nucleation, growth and disassembling of focal adhesions
por: Palumbo, S., et al.
Publicado: (2022) -
Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells
por: Ezratty, Ellen J., et al.
Publicado: (2009) -
Thrombospondin-1 Signaling Through the Calreticulin/LDL Receptor Related Protein 1 Axis: Functions and Possible Roles in Glaucoma
por: Murphy-Ullrich, Joanne E.
Publicado: (2022)