A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation

Activating mutations in FGF receptor 3 (FGFR3) cause several human dwarfism syndromes by affecting both chondrocyte proliferation and differentiation. Using microarray and biochemical analyses of FGF-treated rat chondrosarcoma chondrocytes, we show that FGF inhibits chondrocyte proliferation by init...

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Detalles Bibliográficos
Autores principales: Dailey, Lisa, Laplantine, Emmanuel, Priore, Riccardo, Basilico, Claudio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172997/
https://www.ncbi.nlm.nih.gov/pubmed/12821644
http://dx.doi.org/10.1083/jcb.200302075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172997/
https://www.ncbi.nlm.nih.gov/pubmed/12821644
http://dx.doi.org/10.1083/jcb.200302075

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