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Adhesion-independent mechanism for suppression of tumor cell invasion by E-cadherin
Loss of E-cadherin expression or function in tumors leads to a more invasive phenotype. In this study, we investigated whether the invasion suppressor activity of E-cadherin is mediated directly by tighter physical cell adhesion, indirectly by sequestering β-catenin and thus antagonizing β-catenin/T...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173007/ https://www.ncbi.nlm.nih.gov/pubmed/12810698 http://dx.doi.org/10.1083/jcb.200212033 |