Integrin (α6β4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells

We define a novel mechanism by which integrins regulate growth factor expression and the survival of carcinoma cells. Specifically, we demonstrate that the α6β4 integrin enhances vascular endothelial growth factor (VEGF) translation in breast carcinoma cells. The mechanism involves the ability of th...

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Detalles Bibliográficos
Autores principales: Chung, Jun, Bachelder, Robin E., Lipscomb, Elizabeth A., Shaw, Leslie M., Mercurio, Arthur M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173018/
https://www.ncbi.nlm.nih.gov/pubmed/12105188
http://dx.doi.org/10.1083/jcb.200112015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173018/
https://www.ncbi.nlm.nih.gov/pubmed/12105188
http://dx.doi.org/10.1083/jcb.200112015

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