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Calreticulin reveals a critical Ca(2+) checkpoint in cardiac myofibrillogenesis

Calreticulin (crt) is an ubiquitously expressed and multifunctional Ca(2+)-binding protein that regulates diverse vital cell functions, including Ca(2+) storage in the ER and protein folding. Calreticulin deficiency in mice is lethal in utero due to defects in heart development and function. Herein,...

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Detalles Bibliográficos
Autores principales: Li, Jian, Pucéat, Michel, Perez-Terzic, Carmen, Mery, Annabelle, Nakamura, Kimitoshi, Michalak, Marek, Krause, Karl-Heinz, Jaconi, Marisa E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173019/
https://www.ncbi.nlm.nih.gov/pubmed/12105184
http://dx.doi.org/10.1083/jcb.200204092