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Calreticulin reveals a critical Ca(2+) checkpoint in cardiac myofibrillogenesis
Calreticulin (crt) is an ubiquitously expressed and multifunctional Ca(2+)-binding protein that regulates diverse vital cell functions, including Ca(2+) storage in the ER and protein folding. Calreticulin deficiency in mice is lethal in utero due to defects in heart development and function. Herein,...
Autores principales: | Li, Jian, Pucéat, Michel, Perez-Terzic, Carmen, Mery, Annabelle, Nakamura, Kimitoshi, Michalak, Marek, Krause, Karl-Heinz, Jaconi, Marisa E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173019/ https://www.ncbi.nlm.nih.gov/pubmed/12105184 http://dx.doi.org/10.1083/jcb.200204092 |
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