Ca(2+)-controlled competitive diacylglycerol binding of protein kinase C isoenzymes in living cells

The cellular decoding of receptor-induced signaling is based in part on the spatiotemporal activation pattern of PKC isoforms. Because classical and novel PKC isoforms contain diacylglycerol (DAG)-binding C1 domains, they may compete for DAG binding. We reasoned that a Ca(2+)-induced membrane associ...

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Detalles Bibliográficos
Autores principales: Lenz, Johannes C., Reusch, H. Peter, Albrecht, Nadine, Schultz, Günter, Schaefer, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173038/
https://www.ncbi.nlm.nih.gov/pubmed/12391024
http://dx.doi.org/10.1083/jcb.200203048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173038/
https://www.ncbi.nlm.nih.gov/pubmed/12391024
http://dx.doi.org/10.1083/jcb.200203048

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