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Ca(2+)-controlled competitive diacylglycerol binding of protein kinase C isoenzymes in living cells
The cellular decoding of receptor-induced signaling is based in part on the spatiotemporal activation pattern of PKC isoforms. Because classical and novel PKC isoforms contain diacylglycerol (DAG)-binding C1 domains, they may compete for DAG binding. We reasoned that a Ca(2+)-induced membrane associ...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173038/ https://www.ncbi.nlm.nih.gov/pubmed/12391024 http://dx.doi.org/10.1083/jcb.200203048 |