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Assembly of centrosomal proteins and microtubule organization depends on PCM-1

The protein PCM-1 localizes to cytoplasmic granules known as “centriolar satellites” that are partly enriched around the centrosome. We inhibited PCM-1 function using a variety of approaches: microinjection of antibodies into cultured cells, overexpression of a PCM-1 deletion mutant, and specific de...

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Detalles Bibliográficos
Autores principales: Dammermann, Alexander, Merdes, Andreas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173044/
https://www.ncbi.nlm.nih.gov/pubmed/12403812
http://dx.doi.org/10.1083/jcb.200204023