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Assembly of centrosomal proteins and microtubule organization depends on PCM-1
The protein PCM-1 localizes to cytoplasmic granules known as “centriolar satellites” that are partly enriched around the centrosome. We inhibited PCM-1 function using a variety of approaches: microinjection of antibodies into cultured cells, overexpression of a PCM-1 deletion mutant, and specific de...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173044/ https://www.ncbi.nlm.nih.gov/pubmed/12403812 http://dx.doi.org/10.1083/jcb.200204023 |