Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes

The mechanisms that govern the assembly of nuclear pore complexes (NPCs) remain largely unknown. Here, we have established a role for karyopherins in this process. We show that the yeast karyopherin Kap121p functions in the targeting and assembly of the nucleoporin Nup53p into NPCs by recognizing a...

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Detalles Bibliográficos
Autores principales: Lusk, C. Patrick, Makhnevych, Taras, Marelli, Marcello, Aitchison, John D., Wozniak, Richard W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173048/
https://www.ncbi.nlm.nih.gov/pubmed/12403813
http://dx.doi.org/10.1083/jcb.200203079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173048/
https://www.ncbi.nlm.nih.gov/pubmed/12403813
http://dx.doi.org/10.1083/jcb.200203079

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