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Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes
The mechanisms that govern the assembly of nuclear pore complexes (NPCs) remain largely unknown. Here, we have established a role for karyopherins in this process. We show that the yeast karyopherin Kap121p functions in the targeting and assembly of the nucleoporin Nup53p into NPCs by recognizing a...
Autores principales: | Lusk, C. Patrick, Makhnevych, Taras, Marelli, Marcello, Aitchison, John D., Wozniak, Richard W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173048/ https://www.ncbi.nlm.nih.gov/pubmed/12403813 http://dx.doi.org/10.1083/jcb.200203079 |
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