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Tuberous sclerosis complex tumor suppressor–mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

The evolution of mitogenic pathways has led to the parallel requirement for negative control mechanisms, which prevent aberrant growth and the development of cancer. Principally, such negative control mechanisms are represented by tumor suppressor genes, which normally act to constrain cell prolifer...

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Detalles Bibliográficos
Autores principales: Jaeschke, Anja, Hartkamp, Joerg, Saitoh, Masao, Roworth, Wendy, Nobukuni, Takahiro, Hodges, Angela, Sampson, Julian, Thomas, George, Lamb, Richard
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173059/
https://www.ncbi.nlm.nih.gov/pubmed/12403809
http://dx.doi.org/10.1083/jcb.jcb.200206108