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ECM regulates MT1-MMP localization with β1 or αvβ3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells

Regulation of membrane-type 1 matrix metalloproteinase (MT1-MMP) by different extracellular matrices (ECMs) on human endothelial cells (ECs) has been investigated. First, MT1-MMP is found at the intercellular contacts of confluent ECs grown on β1 integrin–dependent matrix such as type 1 collagen (CO...

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Detalles Bibliográficos
Autores principales: Gálvez, Beatriz G., Matías-Román, Salomón, Yáñez-Mó, María, Sánchez-Madrid, Francisco, Arroyo, Alicia G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173082/
https://www.ncbi.nlm.nih.gov/pubmed/12427871
http://dx.doi.org/10.1083/jcb.200205026