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ECM regulates MT1-MMP localization with β1 or αvβ3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells
Regulation of membrane-type 1 matrix metalloproteinase (MT1-MMP) by different extracellular matrices (ECMs) on human endothelial cells (ECs) has been investigated. First, MT1-MMP is found at the intercellular contacts of confluent ECs grown on β1 integrin–dependent matrix such as type 1 collagen (CO...
Autores principales: | Gálvez, Beatriz G., Matías-Román, Salomón, Yáñez-Mó, María, Sánchez-Madrid, Francisco, Arroyo, Alicia G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173082/ https://www.ncbi.nlm.nih.gov/pubmed/12427871 http://dx.doi.org/10.1083/jcb.200205026 |
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