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A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis
In mammalian cells, the Golgi apparatus undergoes extensive fragmentation during apoptosis. p115 is a key vesicle tethering protein required for maintaining the structural organization of the Golgi apparatus. Here, we demonstrate that p115 was cleaved during apoptosis by caspases 3 and 8. Compared w...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173109/ https://www.ncbi.nlm.nih.gov/pubmed/12438416 http://dx.doi.org/10.1083/jcb.200208013 |