hNuf2 inhibition blocks stable kinetochore–microtubule attachment and induces mitotic cell death in HeLa cells

Identification of proteins that couple kinetochores to spindle microtubules is critical for understanding how accurate chromosome segregation is achieved in mitosis. Here we show that the protein hNuf2 specifically functions at kinetochores for stable microtubule attachment in HeLa cells. When hNuf2...

Descripción completa

Detalles Bibliográficos
Autores principales: DeLuca, Jennifer G., Moree, Ben, Hickey, Jennifer M., Kilmartin, John V., Salmon, E.D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173110/
https://www.ncbi.nlm.nih.gov/pubmed/12438418
http://dx.doi.org/10.1083/jcb.200208159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173110/
https://www.ncbi.nlm.nih.gov/pubmed/12438418
http://dx.doi.org/10.1083/jcb.200208159

Ejemplares similares