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Mossy fiber Zn(2+) spillover modulates heterosynaptic N-methyl-d-aspartate receptor activity in hippocampal CA3 circuits
Although Zn(2+) is contained in large amounts in the synaptic terminals of hippocampal mossy fibers (MFs), its physiological role in synaptic transmission is poorly understood. By using the newly developed high-sensitivity Zn(2+) indicator ZnAF-2, the spatiotemporal dynamics of Zn(2+) was monitored...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173116/ https://www.ncbi.nlm.nih.gov/pubmed/12119362 http://dx.doi.org/10.1083/jcb.200204066 |