Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins

We utilize structurally targeted peptides to identify a “t(C) fusion switch” inherent to the coil domains of the neuronal t-SNARE that pairs with the cognate v-SNARE. The t(C) fusion switch is located in the membrane-proximal portion of the t-SNARE and controls the rate at which the helical bundle t...

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Detalles Bibliográficos
Autores principales: Melia, Thomas J., Weber, Thomas, McNew, James A., Fisher, Lillian E., Johnston, Robert J., Parlati, Frank, Mahal, Lara K., Söllner, Thomas H., Rothman, James E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173141/
https://www.ncbi.nlm.nih.gov/pubmed/12213837
http://dx.doi.org/10.1083/jcb.200112081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173141/
https://www.ncbi.nlm.nih.gov/pubmed/12213837
http://dx.doi.org/10.1083/jcb.200112081

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