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Regulation of membrane fusion by the membrane-proximal coil of the t-SNARE during zippering of SNAREpins
We utilize structurally targeted peptides to identify a “t(C) fusion switch” inherent to the coil domains of the neuronal t-SNARE that pairs with the cognate v-SNARE. The t(C) fusion switch is located in the membrane-proximal portion of the t-SNARE and controls the rate at which the helical bundle t...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173141/ https://www.ncbi.nlm.nih.gov/pubmed/12213837 http://dx.doi.org/10.1083/jcb.200112081 |